Those who have underlying conditions such as hormonal imbalance (diabetes, hypothyroid disorders, pregnancy, etc), rheumatologic disorders, autoimmune diseases, and disorders that involve peripheral nerves etc also predisposes the person to carpal tunnel syndrome. These positive findings unlike other categories of sensory disturbance, are not related to neck pain or restriction of neck movement in those who have repeated wrist and finger movements at work. 脊醫There is increasing evidence that occupational factors, including forceful use of the hands, repetitive use of the hands, and hand-arm vibration, are causes for carpal tunnel syndrome. Tingling and numbness are common symptoms and associated condition in patients who have fibromyalgia or chronic myofascial pain. Together with the sensory deficits in the hands, these patients may also have the possibility of carpal tunnel syndrome. They may have tingling and numbness in the hands with weakness and or atrophy of the short muscles that bring about movements of the thumb. Tingling and numbness are usually due to paroxysmal discharge and extra activity in large myelinated nerve fiber involvement whereas if there is associated pain, this is due to involvement of the small unmyelinated C-fiber nerve axons. Pain and coldness of the upper limb strongly suggest ischemia.